The Potomac River ( ) is in the Mid-Atlantic region of the United States and flows from the Potomac Highlands in West Virginia to Chesapeake Bay in Maryland. It is 405 miles (652 km) long, with a drainage area of 14,700 square miles (38,000 km2), and is the fourth-largest river along the East Coast of the United States. More than 6 million people live within its watershed. The river forms part of the borders between Maryland and Washington, D.C., on the left descending bank, and West Virginia and Virginia on the right descending bank. Except for a small portion of its headwaters in West Virginia, the North Branch Potomac River is considered part of Maryland to the low-water mark on the opposite bank. The South Branch Potomac River lies completely within the state of West Virginia except for its headwaters, which lie in Virginia. All navigable parts of the river were designated as a National Recreation Trail in 2006, and the National Oceanic and Atmospheric Administration (NOAA) designated an 18-square-mile (47 km2) portion of the river in Charles County, Maryland, as the Mallows Bay–Potomac River National Marine Sanctuary in 2019. The river has significant historical and political significance, as the nation's capital of Washington, D.C. is located on its banks, as is Mount Vernon, the home of George Washington. During the American Civil War, the river became the boundary between the Union and the Confederacy, and the Union's largest army, the Army of the Potomac, was named after the river.
