Casa Paoli (English: Paoli House) is a historic house and biographical museum in barrio Cuarto, Ponce, Puerto Rico, in the Ponce Historic Zone. The house is significant as the birthplace of Antonio Paoli (1871–1946), a tenor who was the "first Puerto Rican to reach international recognition in the performing arts" and "one of the most outstanding opera singers of all times". The house was the childhood home of the artist and he was introduced to art and opera at this house during his formative years. In 1987, the house was turned into a museum to honor the career of Antonio Paoli. The building was listed on the U.S. National Register of Historic Places in 2009.

Casa Paoli is located in Ponce, United States. Its specific geographic coordinates are latitude 18.0097 and longitude -66.6127.
The museum was established in 1987, making it a significant historical institution in the region.
biographical museum in Ponce, Puerto Rico... It is a key destination for those interested in culture and history in United States.