The Burdekin River is a river in North and Far North Queensland, Australia. The river rises on the northern slopes of Boulder Mountain at Valley of Lagoons, part of the western slope of the Seaview Range, and flows into the Coral Sea at Upstart Bay over 200 kilometres (124 mi) to the southeast of the source, with a catchment area of approximately 130,000 square kilometres (50,000 sq mi). The Burdekin River is Australia's largest river by (peak) discharge volume. The river was first encountered by Europeans during the expedition led by Ludwig Leichhardt in 1845 and named in honour of Thomas Burdekin, one of the sponsors of the expedition.

